Ferulic Acid → Calebin A
反応式
[C:1]([CH2:14]I)(=[O:13])/[CH:2]=[CH:3]/[C:4]1[CH:12]=[CH:11][C:9]([OH:10])=[C:6]([O:7][CH3:8])[CH:5]=1.[Na].[K].[C:18]([OH:31])(=[O:30])/[CH:19]=[CH:20]/[C:21]1[CH:29]=[CH:28][C:26]([OH:27])=[C:23]([O:24][CH3:25])[CH:22]=1>>[CH3:8][O:7][C:6]1[CH:5]=[C:4](/[CH:3]=[CH:2]/[C:1]([CH2:14][O:31][C:18](/[CH:19]=[CH:20]/[C:21]2[CH:29]=[CH:28][C:26]([OH:27])=[C:23]([O:24][CH3:25])[CH:22]=2)=[O:30])=[O:13])[CH:12]=[CH:11][C:9]=1[OH:10]参加物
5
実験手順
Calebin-A (10a) was prepared by reacting feruloyliodomethane with sodium or potassium salt of ferulic acid with reaction steps and conditions maintained as mentioned in the general synthetic scheme discussed herein above in Para 0010. The yield of the product was 60%.
後処理
- customwith reaction steps and conditions