4-Amino-2-hydroxy-5-nitrobenzoic acid → 4,5-Diamino-2-hydroxybenzoic acid

HRID 2205118ノート

反応式

HRID 2205118 の反応式
[NH2:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:14])[CH:3]=1>CC(O)=O.[Pd]>[NH2:1][C:2]1[C:10]([NH2:11])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:14])[CH:3]=1

参加物

4

反応物 1

HCID 218421914-Amino-2-hydroxy-5-nitrobenzoic acid

生成物 1

HCID 131586084,5-Diamino-2-hydroxybenzoic acid

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒

実験手順

Under an H2(g) atmosphere, a suspension of 4-amino-2-hydroxy-5-nitrobenzoic acid (200 mg, 1.01 mmol, 1.00 equiv) and Pd/C (anhydrous) (0.1 g) in HOAc (15 mL) in a 50-mL round-bottom flask was allowed to react, with stirring, overnight at room temperature. The resulting solution was directly taken on to the next step without further purification.

後処理

  1. customto react
  2. customThe resulting solution was directly taken on to the next step without further purification

出典と根拠

ORDレコード
ord-c8e11cca5aa645de84043ab848f77ef1
出典データセット
uspto-grants-2016_06
特許番号
US09370522B2

反応ノート

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