HCID 10703244、化合物 → HCID 12915443、化合物
反応式
[CH:1]([C:3]1[NH:4][C:5]2[C:10]([C:11]=1[C:12]([O:14][CH3:15])=[O:13])=[CH:9][CH:8]=[CH:7][CH:6]=2)=[CH2:2]>[Pd].CO>[CH2:1]([C:3]1[NH:4][C:5]2[C:10]([C:11]=1[C:12]([O:14][CH3:15])=[O:13])=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH3:2]参加物
4
実験手順
Methyl 2-vinyl-1H-indole-3-carboxylate (80 mg, 0.4 mmol) and 10% palladium on charcoal (100 mg) in methanol (30 mL) were stirred under hydrogen 0.2 MPa at room temperature for 15 hours. The mixture was filterated the solid and concentrated in vacuum to obtain methyl 2-ethyl-1H-indole-3-carboxylate as a white solid (79 mg, 99%) LRMS (M+H+) m/z: calcd 203.1 found 203.
後処理
- concentrationconcentrated in vacuum
出典と根拠
- ORDレコード
- ord-203afddc55f74a9c9c0a0bcc1443ef45
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09371331B2
反応ノート
読み込み中…