Vinyl Acetate → L-Ascorbic acid, 6-acetate
反応式
[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([OH:6])=[C:3]1[OH:4].[C:13](OC=C)(=[O:15])[CH3:14]>C(O)(C)(C)C>[C:13]([O:12][CH2:11][C@H:9]([OH:10])[C@H:7]1[O:8][C:2](=[O:1])[C:3]([OH:4])=[C:5]1[OH:6])(=[O:15])[CH3:14]参加物
4
実験手順
Four grams of the immobilized Lipase PS prepared by the same procedure as in Example 2 was added to 40 ml of a dry t-butanol solution containing 4 g of ascorbic acid and 3 g of vinyl acetate. The reaction was continued for 20 hours at 50° C. The reaction mixture was filtered and concentrated to yield 4.8 g of a crude ascorbic acid-6-acetate. Recrystallization from acetone-benzene gave a crystal with purity of 93%. The water content of the reaction system was 650 ppm.
後処理
- customFour grams of the immobilized Lipase PS prepared by the same procedure as in Example 2
- filtrationThe reaction mixture was filtered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-433b11e2f84e42e3b2bedb133b0519b6
- 出典データセット
- uspto-grants-1995_10
- 特許番号
- US05455174
反応ノート
読み込み中…