1-Benzothiophene-2-carbaldehyde → 2-(4-Bromo-1-methoxynaphthalen-2-yl-methyl)benzo[b]thiophene

HRID 221074

反応式

HRID 221074 の反応式
Br[C:2]1[CH:11]=[C:10]([Br:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]=1[O:13][CH3:14].[S:15]1[C:19]([CH:20]=O)=[CH:18][C:17]2[CH:22]=[CH:23][CH:24]=[CH:25][C:16]1=2>>[S:15]1[C:19]([CH2:20][C:2]2[CH:11]=[C:10]([Br:12])[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[C:3]=2[O:13][CH3:14])=[CH:18][C:17]2[CH:22]=[CH:23][CH:24]=[CH:25][C:16]1=2

参加物

3

反応物 2

HCID 7365001-Benzothiophene-2-carbaldehydeHCID 35720592,4-Dibromo-1-methoxynaphthalene

生成物 1

HCID 666081932-(4-Bromo-1-methoxynaphthalen-2-yl-methyl)benzo[b]thiophene

実験手順

2,4-Dibromo-1-methoxynaphthalene (see J. Clayden, et al. Org. Lett., 5, (2003) 831) and benzo[b]thiophene-2-carboxaldehyde were treated in a manner similar to Reference Example 1 to give the target compound.

後処理

  1. customto give the target compound

出典と根拠

ORDレコード
ord-fa51ac3b14d642d0ae9bd0fbe47c9133
出典データセット
uspto-grants-2012_06
特許番号
US08202984B2

関連ノート

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