Hydrazine hydrate (1:1) → HCID 19375607、化合物

HRID 2211100ノート

反応式

HRID 2211100 の反応式
[CH:1]1[S:5][CH:4]=[CH:3][C:2]=1[C:6]([C:8]1[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=1[C:10](O)=[O:11])=O.O.[NH2:18][NH2:19]>C(O)C>[S:5]1[CH:4]=[CH:3][C:2]([C:6]2[C:8]3[C:9](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:10](=[O:11])[NH:19][N:18]=2)=[CH:1]1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 135547352-(Thiophene-3-carbonyl)benzoic acid

生成物 1

HCID 19375607HCID 19375607、化合物収率 51.4%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1.8 g of o-(3-thenoyl)benzoic acid and 580 mg of hydrazine hydrate were dissolved in 20 ml of ethanol, and the solution was refluxed for 4 hours. After cooling the solution, it was crystallized by adding ether, thereby obtaining 910 mg of 4-(3-thienyl)-1-phthalazinone.

後処理

  1. temperaturethe solution was refluxed for 4 hours
  2. temperatureAfter cooling the solution, it
  3. customwas crystallized
  4. additionby adding ether

出典と根拠

ORDレコード
ord-0c5e4e9cb4ef48c4967f66babd00c4b7
出典データセット
uspto-grants-1995_10
特許番号
US05462941

反応ノート

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