Toluene → HCID 178506761、化合物

HRID 2213931ノート

反応式

HRID 2213931 の反応式
[C:1]([NH-:5])([CH3:4])([CH3:3])[CH3:2].[Li+:6].C1COCC1.C1(C)C=CC=CC=1.[CH3:19][C:20]1[C:25]([CH3:26])=[C:24]([CH3:27])[C:22](=[CH2:23])[C:21]=1[CH3:28]>CCCCC>[C:1]([NH:5][CH2:23][C:22]1([Li:6])[C:24]([CH3:27])=[C:25]([CH3:26])[C:20]([CH3:19])=[C:21]1[CH3:28])([CH3:4])([CH3:3])[CH3:2]

参加物

6

反応物 4

HCID 1140TolueneHCID 8028TetrahydrofuranHCID 144751TetramethylfulveneHCID 10964401Lithium t-butylamide

生成物 1

HCID 178506761HCID 178506761、化合物

試薬・触媒・溶媒 1

HCID 8003Pentane溶媒

実験手順

200 mg (2.53 mmol) of lithium tert-butylamide are dissolved in 50 ml of pentane and 2 ml of THF and admixed with 2.5 g of a 9:1 mixture of toluene and 2,3,4,5-tetramethylfulvene. The reaction solution is stirred overnight, which results in precipitation of the product. The solvent is removed under reduced pressure, the residue is taken up in pure pentane and collected on a frit. After washing twice with 20 ml each time of pentane, the white, pulverulent product is dried under reduced pressure.

後処理

  1. customwhich results in precipitation of the product
  2. customThe solvent is removed under reduced pressure
  3. customcollected on a frit
  4. washAfter washing twice with 20 ml each time of pentane
  5. customthe white, pulverulent product is dried under reduced pressure

出典と根拠

ORDレコード
ord-e803fffe37a7469fa2206e010e17d208
出典データセット
uspto-grants-2006_09
特許番号
US07105690B2

反応ノート

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