Water → 2-(3-Nitrophenyl)-2-oxoethyl acetate
反応式
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([N+:11]([O-:13])=[O:12])[CH:6]=1)=[O:4].[CH3:14][C:15]([O-:17])=[O:16].[Na+].O>CC(CC)=O>[C:15]([O:17][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([N+:11]([O-:13])=[O:12])[CH:6]=1)=[O:4])(=[O:16])[CH3:14]参加物
5
実験手順
2-Bromo-1-(3-nitrophenyl)ethanone (25 g) was dissolved in methylethyl ketone (150 mL). NaOAc (12.5 g) was added and the mixture stirred for 48 hours. Water (100 mL) was added and the reaction mixture extracted with DCM. The DCM layer was dried over Na2SO4 and concentrated to give the title compound (20 g, 87%).
後処理
- extractionthe reaction mixture extracted with DCM
- dry with materialThe DCM layer was dried over Na2SO4
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-125495b67b2042a49067997dd3748cf8
- 出典データセット
- uspto-grants-2012_06
- 特許番号
- US08207167B2
反応ノート
読み込み中…