Benzyl Alcohol → HCID 68856262、化合物
反応式
[C:1]([O:5][C:6](=[O:19])[CH2:7][CH:8]([CH2:12][C:13]([CH3:18])([CH3:17])[CH2:14][CH2:15][CH3:16])C(O)=O)([CH3:4])([CH3:3])[CH3:2].C1C=CC(P(N=[N+]=[N-])(C2C=CC=CC=2)=[O:27])=CC=1.[CH2:37]([OH:44])[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1.CC[N:47]([CH2:50]C)CC>>[C:1]([O:5][C:6](=[O:19])[CH2:7][C@@H:8]([NH:47][C:50]([O:44][CH2:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)=[O:27])[CH2:12][C:13]([CH3:17])([CH3:18])[CH2:14][CH2:15][CH3:16])([CH3:2])([CH3:3])[CH3:4]参加物
5
実験手順
According to example 1, 2.14 g (7.9 mmol) of 2-(2,2-dimethyl-pentyl)-succinic acid 4-tert-butyl ester, 1.7 mL of DPPA, 1.1 mL of Et3N and 2.44 mL of BnOH provided 1.63 g (54.8% in two steps) of the title compound as an oil. 1HNMR (400 MHz; CDCl3): 0.78–0.89 (m, 9H), 1.10–1.30 (m, 5H), 1.36 (s, 9H), 2.39 (t, 2H, J=5 Hz), 4.95–4.05 (m, 1H), 5.00 (s, 2H), 5.09 (d, 1H, J=9.6 Hz), 7.22–7.30 (m, 5H).