Oxalyl chloride → HCID 21942552、化合物

HRID 2216780ノート

反応式

HRID 2216780 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([C:11]#[N:12])[CH:10]=1)[C:5](O)=[O:6].C(Cl)(=O)C([Cl:16])=O>CN(C)C=O>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([C:11]#[N:12])[CH:10]=1)[C:5]([Cl:16])=[O:6]

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 219425953-Chloro-5-cyanobenzoic acid

生成物 1

HCID 21942552HCID 21942552、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

3-Chloro-5-cyanobenzoic acid (0.82 g, 4.97 mmol) was treated with a solution of oxalyl chloride (10 mL of 2.5 M in dichloromethane, 25 mmol) and a catalytic amount of N,N-dimethylformamide. The reaction was stirred at ambient temperature for 2.5 hours. The excess oxalyl chloride was removed in vacuo to afford 3-chloro-5-cyanobenzoyl chloride.

後処理

  1. customThe excess oxalyl chloride was removed in vacuo

出典と根拠

ORDレコード
ord-fb4685cf142c4dc2a5411530da695dcb
出典データセット
uspto-grants-2006_09
特許番号
US07112595B2

反応ノート

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