化工社化工社 化学情報印刷レポート · 研究参考用
Cyclopentanepropanoic acid → N-5-Quinolinyl-cyclopentanepropanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclopentanepropanoic acid | HCID 8818 | — |
| 反応物 | 5-Aminoquinoline | HCID 11911 | — |
| 生成物 | N-5-Quinolinyl-cyclopentanepropanamide | HCID 2107517 | 24.1% |
反応手順
Prepared according to the method of example 18, using 5-quinolinamine (250 mg) and cyclopentanepropanoic acid (270 mg). Purification (HPLC, Symmetry—0.1% aqueous trifluoroacetic acid/acetonitrile) followed by recrystallisation from methanol/ethyl acetate gave the title compound as a colourless solid (112 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07408065B2 |
| 出典データセット | uspto-grants-2008_08 |
| ORD ID | ord-a80433abb70a48ee91e47047b46d9861 |
| 出典メモ | uspto-grants-2008_08 |