3-(4-Hydroxymethylphenyl)acrylic acid ethyl ester → Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate

HRID 2218118ノート

反応式

HRID 2218118 の反応式
[CH2:1]([O:3][C:4](=[O:15])[CH:5]=[CH:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1)[CH3:2].[H][H]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:15])[CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][OH:14])=[CH:11][CH:12]=1)[CH3:2]

参加物

5

反応物 2

HCID 684575823-(4-Hydroxymethylphenyl)acrylic acid ethyl esterHCID 178418361HCID 178418361、化合物

生成物 1

HCID 14839455Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

3-(4-Hydroxymethylphenyl)acrylic acid ethyl ester (P4, 3 g, 14.5 mmol) and palladium on charcoal (0.3 g) in ethanol (30 mL) was stirred for 4 hours under atmospheric pressure of hydrogen. The reaction mixture was filtered through celite (Diatomaceous Earth) and concentrated to afford the title compound as an oil.

後処理

  1. filtrationThe reaction mixture was filtered through celite (Diatomaceous Earth)
  2. concentrationconcentrated

出典と根拠

ORDレコード
ord-88962a19cc68445dac2f54de163f87b2
出典データセット
uspto-grants-2008_08
特許番号
US07410984B2

反応ノート

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