HCID 69275051、化合物 → Methyl 2-(4-chloro-2-propylphenoxy)acetate
反応式
[CH3:1][O:2][C:3](=[O:16])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[CH:8][C:7]=1[CH2:13][CH:14]=[CH2:15]>CCOC(C)=O.[Pt]>[CH3:1][O:2][C:3](=[O:16])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[CH:8][C:7]=1[CH2:13][CH2:14][CH3:15]参加物
4
実験手順
Add 5% Pt/C sulfided (250 mg) to a stirred solution of (2-allyl-4-chloro-phenoxy)-acetic acid methyl ester (587 mg, 2.44 mmol) in EtOAc (10 mL) at ambient temperature under nitrogen. The mixture is flushed with hydrogen for 1 minute then stirred vigorously under hydrogen (balloon) for 1 hour. After filtration and concentration, 584 mg (100% yield) of the title compound is obtained as oil. EIMS: m/z 242 (M+, 35Cl), 244(M+, 37Cl). Analysis for C12H15ClO3: calcd: C, 59.39; H, 6.23; found: C, 59.01; H, 6.14.
後処理
- customat ambient temperature
- customThe mixture is flushed with hydrogen for 1 minute
- filtrationAfter filtration and concentration
出典と根拠
- ORDレコード
- ord-155c818630d544bd9f5ff96a12bbb1d9
- 出典データセット
- uspto-grants-2008_08
- 特許番号
- US07414063B2
反応ノート
読み込み中…