1,3-Dimethyl-1H-pyrazol-5-amine → 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid ethyl ester
反応式
[CH2:1]([O:3][C:4]([C:6]1[C:11](Br)=[CH:10][CH:9]=[C:8]([CH3:13])[N:7]=1)=[O:5])[CH3:2].[NH2:14][C:15]1[N:19]([CH3:20])[N:18]=[C:17]([CH3:21])[CH:16]=1>[Pd]>[CH2:1]([O:3][C:4]([C:6]1[C:11]([NH:14][C:15]2[N:19]([CH3:20])[N:18]=[C:17]([CH3:21])[CH:16]=2)=[CH:10][CH:9]=[C:8]([CH3:13])[N:7]=1)=[O:5])[CH3:2]参加物
4
実験手順
The Pd catalyzed coupling of 3-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester and 5-Amino-1,3-dimethylpyrazole was performed in accordance with the general method of Example 78, step 3 to yield the title compound as a yellow-cristalline solid, MS (ISP): m/e=275.4 (M+H+).
出典と根拠
- ORDレコード
- ord-3bc506501c6c44d08448122599fe95ae
- 出典データセット
- uspto-grants-2008_08
- 特許番号
- US07414060B2
反応ノート
読み込み中…