3-Aminopyridine → 6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester
反応式
[CH2:1]([O:3][C:4]([C:6]1[C:11](Br)=[CH:10][CH:9]=[C:8]([CH3:13])[N:7]=1)=[O:5])[CH3:2].[NH2:14][C:15]1[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=1>[Pd]>[CH2:1]([O:3][C:4]([C:6]1[C:11]([NH:14][C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[CH:10][CH:9]=[C:8]([CH3:13])[N:7]=1)=[O:5])[CH3:2]参加物
4
実験手順
The Pd catalyzed coupling of 3-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester and 3-Amino-pyridine was performed in accordance with the general method of Example 78, step 3 to yield the title compound as a light yellow crystalline solid, MS (ISP): m/e=258.1 (M+H+).
出典と根拠
- ORDレコード
- ord-f939f373b0384a4788082d4e90acb1c3
- 出典データセット
- uspto-grants-2008_08
- 特許番号
- US07414060B2
反応ノート
読み込み中…