2-Butanone oxime → HCID 87736951、化合物
反応式
[CH3:1][C:2](=[N:5][OH:6])[CH2:3][CH3:4].[N:7]([CH2:10][Si:11]([O:16][CH3:17])([O:14][CH3:15])[O:12][CH3:13])=[C:8]=[O:9]>>[CH2:3]([C:2](=[N:5][OH:6])[CH2:1][C:8](=[O:9])[NH:7][CH2:10][Si:11]([O:14][CH3:15])([O:16][CH3:17])[O:12][CH3:13])[CH3:4]参加物
3
実験手順
A stirred mixture conditioned at a temperature of 80° C. of 86.1 g of 2-butanone oxime and 120 mg of “Borchi catalyst” (catalyst VP 0244 from Borchers GmbH, Langenfeld) was admixed over the course of 60 min with 150 g of (isocyanatomethyl)trimethoxysilane. After the end of the addition the mixture was stirred at the temperature stated for a further 60 min and excess 2-butanone oxime was removed by distillation. This gave N-[(trimethoxysilyl)methyl]carbamoylmethyl ethyl ketone oxime in quantitative yield with a purity of >95% (analysis by 29Si and 1H NMR).
後処理
- additionAfter the end of the addition the mixture
- customexcess 2-butanone oxime was removed by distillation