Triphenylphosphine → [(1-ethyl-1H-imidazol-5-yl)methyl](triphenyl)phosphonium chloride hydrochloride
反応式
[ClH:1].[Cl:2][CH2:3][C:4]1[N:8]([CH2:9][CH3:10])[CH:7]=[N:6][CH:5]=1.[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(#N)C>[ClH:2].[Cl-:1].[CH2:9]([N:8]1[C:4]([CH2:3][P+:17]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[CH:5][N:6]=[CH:7]1)[CH3:10]参加物
4
実験手順
5-Chloromethyl-1-ethyl-1H-imidazole hydrochloride (6.00 g), triphenylphosphine (25.73 g) and acetonitrile (80 mL) were heated under reflux overnight. After cooling, the precipitated crystals were collected by filtration and washed with hexane to give [(1-ethyl-1H-imidazol-5-yl)methyl](triphenyl)phosphonium chloride hydrochloride as colorless crystals (10.50 g, yield 72%). melting point: 287-289° C.