Ethyl Acrylate → ethyl (1H-1,2,3-triazol-1-yl)propanoate
反応式
[NH:1]1[CH:5]=[CH:4][N:3]=[N:2]1.[C:6]([O:10][CH2:11][CH3:12])(=[O:9])[CH:7]=[CH2:8]>N1C=CC=CC=1>[N:1]1([CH:7]([CH3:8])[C:6]([O:10][CH2:11][CH3:12])=[O:9])[CH:5]=[CH:4][N:3]=[N:2]1参加物
4
反応条件
- 温度
- 90 °C
実験手順
A mixture of 1,2,3-triazole (5 g, 72.4 mmol) and ethyl acrylate (7.8 ml, 72.4 mmol) containing pyridine (50 drops) was heated at 90° C. for 4 hours. After cooling, the volatiles were removed under vacuum and the residue was purified by column chromatography eluting with methylene chloride/ether to give ethyl (1H-1,2,3-triazol-1-yl)propanoate (8.96 g, 73%).
後処理
- temperatureAfter cooling
- customthe volatiles were removed under vacuum
- customthe residue was purified by column chromatography
- washeluting with methylene chloride/ether
出典と根拠
- ORDレコード
- ord-9cff62d587e04cbab690f0b93bcf2acd
- 出典データセット
- uspto-grants-2008_05
- 特許番号
- US07371765B2
反応ノート
読み込み中…