2,6-Dimethylbenzoic acid → 2,6-Dimethylbenzoyl chloride

HRID 222392

反応式

HRID 222392 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:14])=O>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([Cl:14])=[O:5]

参加物

4

反応物 2

HCID 124392,6-Dimethylbenzoic acidHCID 24386Thionyl Chloride

生成物 1

HCID 890962,6-Dimethylbenzoyl chloride

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒2 回

実験手順

To a mixture of 2,6-dimethylbenzoic acid (3 g; 0.02 mol) in toluene (50 ml) was added thionyl chloride (3.6 ml; 0.05 mol). The mixture thus obtained was refluxed for 2 hours. The solvent and the excess thionyl chloride were then evaporated off under reduced pressure. The residue thus obtained was taken up in toluene (50 ml) three times and evaporated under reduced pressure. The product thus obtained (3.6 g) was used without further purification.

後処理

  1. customThe mixture thus obtained
  2. temperaturewas refluxed for 2 hours
  3. customThe solvent and the excess thionyl chloride were then evaporated off under reduced pressure
  4. customThe residue thus obtained
  5. customevaporated under reduced pressure
  6. customThe product thus obtained (3.6 g)
  7. customwas used without further purification

出典と根拠

ORDレコード
ord-396b2865b8034330a6403c08a42ebb9e
出典データセット
uspto-grants-2012_06
特許番号
US08207214B2

関連ノート

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