Methyl triflate → N-[2-(pyridin-2-ylsulfanyl)ethyl)thioacetimidic acid methyl ester
反応式
F[C:2](F)(F)S(OC)(=O)=O.[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[S:16][CH2:17][CH2:18][NH:19][C:20](=[S:22])[CH3:21]>C(Cl)Cl>[CH3:2][S:22][C:20](=[N:19][CH2:18][CH2:17][S:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][N:10]=1)[CH3:21]参加物
4
実験手順
Add methyl trifluoromethanesulfonate (65.5 mg, 0.4 mmol) to a solution of N-(2-(pyridin-2-ylsulfanyl)ethyl)thioacetamide (85.0 mg, 0.4 mmol) in methylene chloride (10 mL) under nitrogen. Stir the reaction mixture at room temperature for 5 minutes and remove the solvent under reduced pressure to give N-[2-(pyridin-2-ylsulfanyl)ethyl)thioacetimidic acid methyl ester (0.4 mmol) as a colorless oil. MS (ES): m/z 227 (M+H).
後処理
- customremove the solvent under reduced pressure
出典と根拠
- ORDレコード
- ord-89fda9096085474099d5ac82eef158e6
- 出典データセット
- uspto-grants-2008_05
- 特許番号
- US07378447B2
反応ノート
読み込み中…