反応式
[C:1]([OH:7])(=O)[CH2:2][C:3]([OH:5])=[O:4].[NH2:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=O.N1CCCCC1.Cl>N1C=CC=CC=1>[C:3]([C:2]1[C:1](=[O:7])[NH:8][C:9]2[C:10]([CH:11]=1)=[CH:13][CH:14]=[CH:15][CH:16]=2)([OH:5])=[O:4]参加物
6
反応条件
- 温度
- 90 °C
実験手順
2 Grams of malonic acid was dissolved in 15 ml of pyridine, then 1.2 g of o-aminobenzaldehyde and 2 ml of piperidine were added thereto, and the mixture was stirred at 90° C. for 5 hours. The reaction mixture was poured in an aqueous solution of hydrochloric acid and the crystals precipitated were collected by filtration. Recrystallized from methanol-chloroform to obtain 1.2 g of 3-carboxycarbostyril in the form of colorless needle-like crystals.
後処理
- customthe crystals precipitated
- filtrationwere collected by filtration
- customRecrystallized from methanol-chloroform
出典と根拠
- ORDレコード
- ord-e9275bd61d724c5faffa0e0519491c3e
- 出典データセット
- uspto-grants-1994_09
- 特許番号
- USRE034722
関連ノート
読み込み中…