alpha-Oxo-4-[[(4phenoxy)butyl]oxy]benzeneacetic acid methyl ester → alpha-Oxo-4-[[(4-phenoxy)butyl]oxy]benzeneacetic acid
反応式
C[O:2][C:3](=[O:24])[C:4](=[O:23])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:7][CH:6]=1>CO.[OH-].[Na+]>[O:23]=[C:4]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][O:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:7][CH:6]=1)[C:3]([OH:24])=[O:2]参加物
4
実験手順
A mixture of alpha-oxo-4-[[(4-phenoxy)butyl]oxy]benzeneacetic acid methyl ester (0.85 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided material which was crystallized from diethyl ether-hexane to give 0.7 g of colorless alpha-oxo-4-[[(4-phenoxy)butyl]oxy]benzeneacetic acid, mp 103°-105° C.