Water → 2-Ethylamino-3-nitropyridine
反応式
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH2:11]([NH2:13])[CH3:12].O>C1COCC1>[CH2:11]([NH:13][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1)[CH3:12]参加物
5
実験手順
To a solution of 2-chloro-3-nitropyridine (51 g, 325 mmol) in THF (650 mL) was added a 2 M solution of ethylamine in THF (365 mL, 731 mmol). The reaction was stirred at room temperature overnight. The reaction mixture was poured into water (˜1.5 L) and the resulting solid was filtered and dried under reduced pressure to give the title compound (52 g).
後処理
- filtrationthe resulting solid was filtered
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-6dbf7c26a3a34e8b80800167216e79d0
- 出典データセット
- uspto-grants-2002_07
- 特許番号
- US06420359B1
反応ノート
読み込み中…