Sulfuric Acid → Benzene, 1-methyl-4-[1-(chloromethyl)-1-methylethyl]

HRID 223114ノート

反応式

HRID 223114 の反応式
[CH2:1]([Cl:5])[C:2](=[CH2:4])[CH3:3].S(=O)(=O)(O)O.[C:11]1([CH3:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH3:4][C:2]([C:14]1[CH:15]=[CH:16][C:11]([CH3:17])=[CH:12][CH:13]=1)([CH3:3])[CH2:1][Cl:5]

参加物

4

反応物 3

HCID 1118Sulfuric AcidHCID 1140TolueneHCID 112413-Chloro-2-methyl-1-propene

生成物 1

HCID 524329Benzene, 1-methyl-4-[1-(chloromethyl)-1-methylethyl]収率 85%

実験手順

24 g Methallyl chloride is added to a mixture of 92 g toluene and 49 g concentrated sulphuric acid, keeping the temperature at 40° C. No exothermal reaction occurs. Subsequently the reaction mixture is stirred during half an hour, after which the layers are separated. The organic layer is washed neutral with soda solution, dried on MgSO4 and evaporated. The residue is distilled under diminished pressure to obtain 2-methyl-2-(p-tolyl)-propyl chloride (p-methyl-neophyl chloride) in a yield of 85%.

後処理

  1. customat 40° C
  2. customNo exothermal reaction
  3. customafter which the layers are separated
  4. washThe organic layer is washed neutral with soda solution
  5. customdried on MgSO4
  6. customevaporated
  7. distillationThe residue is distilled under diminished pressure

出典と根拠

ORDレコード
ord-ffca0aac55ea4cc9b8da7f6f473e096d
出典データセット
uspto-grants-1982_10
特許番号
US04352748

反応ノート

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