Ammonia → 2,3,5-Trimethylpyridine

HRID 2231948ノート

反応式

HRID 2231948 の反応式
Cl[C:2]1[C:7]([CH3:8])=[C:6](Cl)[N:5]=[C:4]([CH3:10])[C:3]=1[CH3:11].N.[H][H]>C(O)C.[Pd]>[CH3:10][C:4]1[C:3]([CH3:11])=[CH:2][C:7]([CH3:8])=[CH:6][N:5]=1

参加物

6

反応物 3

HCID 222AmmoniaHCID 27791392,4-Dichloro-3,5,6-trimethylpyridineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 127592,3,5-Trimethylpyridine

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

20 g 4,6-dichloro-2,3,5 trimethylpyridine was dissolved in 150 ml ethanol and 1 g 10% Pd/C and 10 ml conc. aqueous ammonia. The hydrogenation was performed at 3 bar for 3 hrs when the calculated amount of hydrogen had been adsorbed. Evaporation of solvent gave the 2,3,5-trimethylpyridine.

後処理

  1. customEvaporation of solvent

出典と根拠

ORDレコード
ord-b1bbbf7fd11b48a6b34e18dd717dbbfa
出典データセット
uspto-grants-1988_11
特許番号
US04785113

反応ノート

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