Carbon Dioxide → HCID 19851597、化合物

HRID 223198ノート

反応式

HRID 223198 の反応式
[Cl:1][C:2]1[C:7]2[C:8](=[O:20])[N:9]([CH3:19])[CH2:10][C:11]3[N:12]([CH:13]=[N:14][C:15]=3C(O)=O)[C:6]=2[CH:5]=[CH:4][CH:3]=1.C(=O)=O>C(Cl)(Cl)Cl>[Cl:1][C:2]1[C:7]2[C:8](=[O:20])[N:9]([CH3:19])[CH2:10][C:11]3[N:12]([CH:13]=[N:14][CH:15]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 280Carbon DioxideHCID 145904217-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid

生成物 1

HCID 19851597HCID 19851597、化合物

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

2.69 g of 7-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid are heated to 290°. After completion of the carbon dioxide evolution, the brown melt is cooled and taken up in chloroform. This solution is filtered over a silica gel column and evaporated. There is obtained 7-chloro-4,5-dihydro-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one of melting point 200°-201°.

後処理

  1. filtrationThis solution is filtered over a silica gel column
  2. customevaporated

出典と根拠

ORDレコード
ord-5d7bfbf49b734ae898964cf7bb98911d
出典データセット
uspto-grants-1982_10
特許番号
US04352818

反応ノート

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