m-Chloroperbenzoic acid → HCID 21283336、化合物

HRID 2232233ノート

反応式

HRID 2232233 の反応式
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]2[C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[C:23]3=[N:30][N:31]=[C:32]([S:33][CH3:34])[N:22]3[N:21]=2)=[CH:16][CH:15]=1>C(Cl)Cl>[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]2[C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[C:23]3=[N:30][N:31]=[C:32]([S:33]([CH3:34])=[O:9])[N:22]3[N:21]=2)=[CH:16][CH:15]=1

参加物

4

反応物 2

HCID 70297m-Chloroperbenzoic acidHCID 21283334HCID 21283334、化合物

生成物 1

HCID 21283336HCID 21283336、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

3-Chloroperbenzoic acid (2.2 g) is added to a solution of 6-(4-methoxyphenyl)-3-(methylthio)-1,2,4-triazolo[3,4-a]phthalazine (4 g) in methylene chloride (120 ml) and the obtained mixture is stirred at room temperature for 5 hours. The solution is washed with sodium metabisulfite first and then with sodium bicarbonate. The organic solution is then dried over MgSO4 and concentrated to dryness by evaporating off the solvent. The residue thus obtained is crystallized from ethanol yielding 4 g of the compound of the title. M.p. 201°-03° C.

後処理

  1. washThe solution is washed with sodium metabisulfite first
  2. dry with materialThe organic solution is then dried over MgSO4
  3. concentrationconcentrated to dryness
  4. customby evaporating off the solvent
  5. customThe residue thus obtained
  6. customis crystallized from ethanol yielding 4 g of the compound of the title

出典と根拠

ORDレコード
ord-350290d39b944b0786a02776330d47bd
出典データセット
uspto-grants-1988_11
特許番号
US04788186

反応ノート

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