Imipramine → CID 16052002

HRID 2237400ノート

反応式

HRID 2237400 の反応式
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][N:7]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH2:15][CH2:14][C:13]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]1=2)[CH3:3].[CH:22]1[CH:23]=[CH:24][C:25]2[C:26](=[CH:28][C:29]([C:48]([OH:50])=[O:49])=[C:30]([OH:47])[C:31]=2[CH2:32][C:33]2[C:42]([OH:43])=[C:41]([C:44]([OH:46])=[O:45])[CH:40]=[C:39]3[C:34]=2[CH:35]=[CH:36][CH:37]=[CH:38]3)[CH:27]=1.C1C=C2C=C(C(O)=O)C(O)=C(CC3C4C(=CC=CC=4)C=C(C(O)=O)C=3O)C2=CC=1.[Na+]>O>[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][N:7]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=2[CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]1=2)[CH3:3].[CH:22]1[CH:23]=[CH:24][C:25]2[C:26](=[CH:28][C:29]([C:48]([OH:50])=[O:49])=[C:30]([OH:47])[C:31]=2[CH2:32][C:33]2[C:42]([OH:43])=[C:41]([C:44]([OH:46])=[O:45])[CH:40]=[C:39]3[C:34]=2[CH:35]=[CH:36][CH:37]=[CH:38]3)[CH:27]=1

参加物

5

反応物 3

HCID 3696Imipramine3 回HCID 8546Pamoic Acid2 回HCID 10179807Disodium methylenebis(2-hydroxy-3-naphthoate)

生成物 1

HCID 16052002CID 16052002

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The pamoate salt of Imipramine can be prepared by treatment of Imipramine with pamoic salt or pamoic acid in a solvent or solvent mix. Imipramine pamoate was prepared by adding a solution of imipramine in an appropriate solvent, e.g. acidic water, to a solution of disodium pamoate, pamoic acid or other pamoate salt and stirred resulting in precipitation of the salt.

後処理

  1. additionmix
  2. customresulting in precipitation of the salt

出典と根拠

ORDレコード
ord-c01f26a100e645d6b8259bc50ec03d4a
出典データセット
uspto-grants-2010_05
特許番号
US07718649B1

反応ノート

読み込み中…