Sodium Iodide → Benzene, (8-iodooctyl)-

HRID 22430ノート

反応式

HRID 22430 の反応式
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[I-:16].[Na+]>CC(C)=O>[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][I:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 5238Sodium IodideHCID 2901511-Chloro-8-phenyloctane

生成物 1

HCID 10947018Benzene, (8-iodooctyl)-

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A mixture of 8-phenyloctyl chloride (4.4 g), sodium iodide (5.34 g) and acetone (20 ml) was heated under reflux for 20 hours. Evaporated, water (20 ml) added and extracted with diethyl ether (20 ml). The extracts were dried, filtered and evaporated to a pale yellow liquid (5.5 g). Distilled to give 8-phenyloctyl iodide, b.p. 200° C. (air bath temperature) at 0.1 mBar.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 20 hours
  3. customEvaporated
  4. additionwater (20 ml) added
  5. extractionextracted with diethyl ether (20 ml)
  6. customThe extracts were dried
  7. filtrationfiltered
  8. customevaporated to a pale yellow liquid (5.5 g)
  9. distillationDistilled

出典と根拠

ORDレコード
ord-fcbfdb0afc3740d1a45acd0665c464c3
出典データセット
uspto-grants-1995_06
特許番号
US05428065

反応ノート

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