(3,4-Dimethoxyphenyl)acetic acid → (3,4-Dimethoxyphenyl)acetyl chloride
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][C:12]([OH:14])=O)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].S(Cl)([Cl:17])=O>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][C:12]([Cl:17])=[O:14])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]参加物
4
実験手順
3,4-Dimethoxyphenylacetic acid (6.47 g, 0.033 mole) was dissolved in 50 ml of dry benzene and refluxed for 2 hr. with excess thionyl chloride (25 ml). The solvent and SOCl2 were removed on a rotary evaporator. Two additional quantities of dry benzene were added to the residue, followed by rotary evaporation which yielded 3,4-dimethoxyphenylacetyl chloride.
後処理
- temperaturerefluxed for 2 hr
- customThe solvent and SOCl2 were removed on a rotary evaporator
- additionTwo additional quantities of dry benzene were added to the residue
- customfollowed by rotary evaporation which
出典と根拠
- ORDレコード
- ord-443b7a78d92843cb864c7a958b3edf6d
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04232014
反応ノート
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