Hydrochloric Acid → HCID 178492091、化合物
反応式
[NH2:1][C:2](=[S:16])[NH:3][N:4]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1)[C:5](=O)[CH3:6].[OH-].[Na+].CO.Cl>O>[CH3:15][O:14][C:11]1[CH:12]=[CH:13][C:8]([N:4]2[C:5]([CH3:6])=[N:1][C:2]([SH:16])=[N:3]2)=[CH:9][CH:10]=1参加物
6
実験手順
A mixture of 14.5 parts of acetic acid 2-(aminothioxomethyl)-1-(4-methoxyphenyl)hydrazide, 5 parts of sodium hydroxide and 80 parts of methanol is stirred and refluxed for 30 minutes. The reaction mixture is cooled and water is added. The whole is adjusted to pH 5 with a hydrochloric acid solution. The precipitated product is filtered off and dried, yielding 12.3 parts (91%) of 1-(4-methoxyphenyl)-5-methyl-1H-1,2,4-triazole-3-thiol.
後処理
- temperaturerefluxed for 30 minutes
- temperatureThe reaction mixture is cooled
- filtrationThe precipitated product is filtered off
- customdried
出典と根拠
- ORDレコード
- ord-b1fe218ebb514a5384a3e811e1e81993
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04232034
反応ノート
読み込み中…