Imidazole → HCID 12786183、化合物
反応式
[OH:1][C:2]([CH3:11])([C:6](=[CH2:10])[CH2:7][CH2:8][CH3:9])[CH2:3][C:4]#[CH:5].N1C=CN=C1.CN(C)C=O.Cl[Si:23]([CH3:26])([CH3:25])[CH3:24]>O>[CH3:11][C:2]([O:1][Si:23]([CH3:26])([CH3:25])[CH3:24])([C:6](=[CH2:10])[CH2:7][CH2:8][CH3:9])[CH2:3][C:4]#[CH:5]参加物
6
実験手順
To a solution of 25.77 g. of 4-hydroxy-4-methyl-5-methylene-1-octyne and 28.6 g. of imidazole in 50 ml. of dimethylformamide is added 22.9 g. of chlorotrimethylsilane. The mixture is stirred at room temperature for 40 minutes, poured into cold water and extracted with petroleum ether. The extract is washed with water and saturated sodium bicarbonate solution, dried over magnesium sulfate and the solvent is removed. The residue is distilled and the desired product recovered at 85°-87° C. (0.45 mm.) as a colorless liquid.
後処理
- extractionextracted with petroleum ether
- washThe extract is washed with water and saturated sodium bicarbonate solution
- dry with materialdried over magnesium sulfate
- customthe solvent is removed
- distillationThe residue is distilled
- customthe desired product recovered at 85°-87° C. (0.45 mm.) as a colorless liquid
出典と根拠
- ORDレコード
- ord-6b20ba9a1a3041aa9d47ff2a395d4454
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04232166
反応ノート
読み込み中…