Ethylenediamine → HCID 68544128、化合物
反応式
Br[CH2:2][CH2:3][N:4]1[CH:8]=[CH:7][CH:6]=[N:5]1.[CH2:9]([NH2:12])[CH2:10][NH2:11]>O1CCCC1.O>[N:4]1([CH2:3][CH2:2][N:11]=[CH:10][CH2:9][NH2:12])[CH:8]=[CH:7][CH:6]=[N:5]1参加物
5
実験手順
A solution of 1-(2-bromoethyl)pyrazole [6d] (12 mmol) in tetrahydrofuran was added dropwise to a solution of ethylenediamine (0.24 mol) in water. The mixture was refluxed for 4 hours. The THF was removed under vacuum and the water phase was washed with dichloromethane. After drying under vacuum resulted a yellow oil which was formulated as pz(CH2)2NH(CH2)2NH2 (1). Yield: 50%
後処理
- temperatureThe mixture was refluxed for 4 hours
- customThe THF was removed under vacuum
- washthe water phase was washed with dichloromethane
- customAfter drying under vacuum
- customresulted a yellow oil which
出典と根拠
- ORDレコード
- ord-7c8eda593d6c4b59a76a846090f7cdc6
- 出典データセット
- uspto-grants-2010_03
- 特許番号
- US07682601B2
反応ノート
読み込み中…