Hydroxylamine → 2-Chloro-N'-hydroxy-4-[(methylsulfonyl)amino]benzenecarboximidamide
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][S:11]([CH3:14])(=[O:13])=[O:12])[CH:5]=[CH:6][C:7]=1[C:8]#[N:9].[NH2:15][OH:16]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][S:11]([CH3:14])(=[O:13])=[O:12])[CH:5]=[CH:6][C:7]=1[C:8](=[N:15][OH:16])[NH2:9]参加物
4
反応条件
- 温度
- 90 °C
実験手順
To a stirred solution of the product from Step A (0.13 g, 0.565 mmol) in ethanol (3 mL) was added hydroxylamine (50% in water, 1.0 mL). The reaction was heated at 90° C. for 2 h. The reaction was then concentrated to give the desired product.
後処理
- concentrationThe reaction was then concentrated
出典と根拠
- ORDレコード
- ord-29c660b8b31b4cfb89eb3c7c518f418c
- 出典データセット
- uspto-grants-2010_03
- 特許番号
- US07687492B2
反応ノート
読み込み中…