Hydrazinecarboxaldehyde → 3-methylbenzothiazol-2(3H)-one hydrazone

HRID 224682

反応式

HRID 224682 の反応式
C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH3:12][N+:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[S:15][C:14]=1SC.C([NH:26][NH2:27])=O>O>[CH3:12][N:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[S:15][C:14]1=[N:26][NH2:27]

参加物

4

反応物 2

HCID 12229HydrazinecarboxaldehydeHCID 41464Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1)

生成物 1

HCID 143193-methylbenzothiazol-2(3H)-one hydrazone

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

Into a flask equipped with a reflux condenser and magnetic stirrer is charged 50 ml water. Then 28.1 g (0.076 moles) 3-methyl-2-methylthiobenzothiazolium p-toluene sulfonate is dissolved with slight heating. A solution of 9.1 g (0.15 moles) formylhydrazine in 25 ml of water then is added and the mixture is heated at reflux for 15 minutes. The cooled suspension is made acidic until a clear solution results, then made basic. The product precipitates and is filtered, giving 9.1 g (66%), m.p. 134° C.

後処理

  1. customInto a flask equipped with a reflux condenser and magnetic stirrer
  2. temperaturethe mixture is heated
  3. temperatureat reflux for 15 minutes
  4. customresults
  5. customThe product precipitates
  6. filtrationis filtered
  7. customgiving 9.1 g (66%), m.p. 134° C.

出典と根拠

ORDレコード
ord-ddf6340fa1db41a3aaf7dccd81bf8f7c
出典データセット
uspto-grants-1980_11
特許番号
US04233442

関連ノート

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