Isopropylamine → HCID 14990558、化合物

HRID 2248309ノート

反応式

HRID 2248309 の反応式
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[O:9])=[CH:4][C:3]=1[N+:17]([O-:19])=[O:18].[CH3:20][CH:21]([NH2:23])[CH3:22]>O>[F:16][C:13]1[CH:14]=[CH:15][C:10]([C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:23][CH:21]([CH3:22])[CH3:20])=[C:3]([N+:17]([O-:19])=[O:18])[CH:4]=2)=[O:9])=[CH:11][CH:12]=1

参加物

4

反応物 2

HCID 6363IsopropylamineHCID 30155644-Chloro-4'-fluoro-3-nitrobenzophenone

生成物 1

HCID 14990558HCID 14990558、化合物収率 97.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of 14 parts of (4-chloro-3-nitrophenyl) (4-fluorophenyl)-methanone in 69 parts of 2-propanamine was stirred overnight at reflux temperature. The reaction mixture was poured into water. The precipitate was filtered off and washed with water, dried, filtered and evaporated, yielding 14.7 parts (97.2%) of (4-fluorophenyl) [4-[(1-methylethyl)-amino]-3-nitrophenyl]methanone as a residue (int. 1).

後処理

  1. temperatureat reflux temperature
  2. filtrationThe precipitate was filtered off
  3. washwashed with water
  4. customdried
  5. filtrationfiltered
  6. customevaporated

出典と根拠

ORDレコード
ord-14fbbd2795cd443084668a93f1c7d33e
出典データセット
uspto-grants-1991_08
特許番号
US05039677

反応ノート

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