Sodium Carbonate → HCID 10107780、化合物
反応式
C([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7](/[CH:11]=[CH:12]/[C:13]2[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][C:17]([Cl:23])=[CH:18][CH:19]=3)[N:14]=2)[CH:6]=1)(=O)C.C(=O)([O-])[O-].[Na+].[Na+]>CO>[Cl:23][C:17]1[CH:16]=[C:15]2[C:20]([CH:21]=[CH:22][C:13](/[CH:12]=[CH:11]/[C:7]3[CH:6]=[C:5]([OH:4])[CH:10]=[CH:9][CH:8]=3)=[N:14]2)=[CH:19][CH:18]=1参加物
4
実験手順
A mixture of (E)-3-(7-chloro-2-quinolinylethenyl)phenyl acetate (7.4 g, 22.9 mmol) and anhydrous sodium carbonate (606 mg, 5.7 mmol) in 135 ml of methanol is stirred at room temperature for 36 hours. pH 7 buffer (250 ml) is added and the precipitated solid filtered and dried to afford (E)-3-(7-chloro-2-quinolinylethenyl)phenol which is used directly in the next step.
後処理
- additionpH 7 buffer (250 ml) is added
- filtrationthe precipitated solid filtered