Benzoic Acid → Methanone, (2,5-dimethylphenyl)phenyl-
反応式
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.FC(F)(F)S(O)(=O)=O.[CH3:18][C:19]1[CH:20]=[CH:21][C:22]([CH3:25])=[CH:23][CH:24]=1>>[CH3:18][C:19]1[CH:20]=[CH:21][C:22]([CH3:25])=[CH:23][C:24]=1[C:1]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)=[O:9]参加物
4
実験手順
Benzoic acid (20 g, 0.16 mole), p-xylene (100 mL), and trifluoromethanesulfonic acid (5 mL) were heated at reflux in a 300 mL flask equipped with a Dean-Stark trap. After 16 hours, the mixture was extracted with 100 mL of 6% aqueous sodium hydroxide, washed with water, dried over magnesium sulfate and evaporated to give 15.4 g (0.073 mole) of 2,5-dimethylbenzophenone. The aqueous sodium hydroxide extract was acidified to give 8.1 g (0.066 mole) of unreacted benzoic acid.
後処理
- temperatureat reflux in a 300 mL flask
- customequipped with a Dean-Stark trap
- extractionthe mixture was extracted with 100 mL of 6% aqueous sodium hydroxide
- washwashed with water
- dry with materialdried over magnesium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-744cf8b4a7614f11bd058ba5066fff31
- 出典データセット
- uspto-grants-1991_08
- 特許番号
- US05041616
反応ノート
読み込み中…