Acetic Anhydride → HCID 86745022、化合物

HRID 2249207ノート

反応式

HRID 2249207 の反応式
[CH3:1][O:2][C:3]1[CH:9]=[C:8]([OH:10])[C:7]([CH2:11][CH:12]=[C:13]([CH3:15])[CH3:14])=[CH:6][C:4]=1[OH:5].[C:16]([O:19]C(=O)C)(=[O:18])[CH3:17]>N1C=CC=CC=1>[C:16]([OH:19])(=[O:18])[CH3:17].[C:16]([OH:19])(=[O:18])[CH3:17].[CH3:1][O:2][C:3]1[CH:9]=[C:8]([OH:10])[C:7]([CH2:11][CH:12]=[C:13]([CH3:15])[CH3:14])=[CH:6][C:4]=1[OH:5]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 3344962-Methoxy-5-(3-methylbut-2-enyl)benzene-1,4-diol

生成物 1

HCID 86745022HCID 86745022、化合物収率 78%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A mixture of 2-methoxy-5-(3-methyl-2-butenyl)hydroquinone (2.35 g) and acetic anhydride (4.6 g) in dry pyridine (20 ml) was stirred for 2 hours at ambient temperature. The mixture was poured into ice water (50 ml) and the separated oil was extracted twice with diethyl ether. The combined extracts were washed twice with diluted hydrochloric acid, dried, and concentrated in vacuo to give a white solid, which was recrystallized from n-hexane to yield 2-methoxy-5-(3-methyl-2-butenyl)hydroquinone diacetate as white crystals (2.89 g).

後処理

  1. extractionthe separated oil was extracted twice with diethyl ether
  2. washThe combined extracts were washed twice with diluted hydrochloric acid
  3. customdried
  4. concentrationconcentrated in vacuo
  5. customto give a white solid, which
  6. customwas recrystallized from n-hexane

出典と根拠

ORDレコード
ord-7142702301024cee9392a938f4ca62b5
出典データセット
uspto-grants-1991_08
特許番号
US05043354

反応ノート

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