1-Amino-4-hydroxyanthraquinone → 1-Amino-2-bromo-4-hydroxyanthraquinone

HRID 225033

反応式

HRID 225033 の反応式
[NH2:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[CH:5]=[CH:4][C:3]=1[Br:18].NC1C2C(=[O:34])C3C(=CC=CC=3)C(=O)C=2C(Br)=CC=1.NC1C2C(=O)C3C(=CC=CC=3)C(=O)C=2C(O)=CC=1>NC1C2C(=O)C3C(=CC=CC=3)C(=O)C=2C=CC=1O>[NH2:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]([OH:34])=[CH:4][C:3]=1[Br:18]

参加物

5

反応物 3

HCID 83231-Amino-4-hydroxyanthraquinoneHCID 2368951-Amino-2-bromoanthraquinoneHCID 6273261-Amino-4-bromoanthraquinone

生成物 1

HCID 83201-Amino-2-bromo-4-hydroxyanthraquinone

試薬・触媒・溶媒 1

HCID 34781731-Amino-2-hydroxyanthra-9,10-quinone溶媒

実験手順

The progress of the bromination may be followed by thin layer chromatography or high pressure liquid chromatography so as to insure that the byproducts, 1-amino-2-bromoanthraquinone and 1-amino-4-bromoanthraquinone, represent less than 1% of the product mixture. This is essential, since hydroxylation of these two products results in 1-amino-2-hydroxyanthraquinone and 1-amino-4-hydroxyanthraquinone respectively. Both products are isolated along with the desired 1-amino-2-bromo-4-hydroxyanthraquinone and therefore give rise to a product with unsatisfactory quality.

出典と根拠

ORDレコード
ord-323b5bf544664fefa041dc236dcb1427
出典データセット
uspto-grants-1980_11
特許番号
US04235789

関連ノート

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