関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 2-Indancarboxylic Acid | HCID 575777 | — |
| 生成物 | Methyl indane-2-carboxylate | HCID 9964238 | — |
反応手順
Dissolve 2-carboxy-indan (2.5 g, 15.4 mmol) in methanol and cool to 0° C. Saturate with hydrochloride gas then add 2,2-dimethoxypropane (2-3 mL). Stir overnight then evaporate the solvent in vacuo. Purify by silica gel chromatography (2:1 methylene chloride/hexane) to give 2-carbomethoxy-indan as a water white oil. (2.04 g, 75%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05428158 |
|---|
| 出典データセット | uspto-grants-1995_06 |
|---|
| ORD ID | ord-38f037c84c494d80b5396fab8d9bdc3b |
|---|
| 出典メモ | uspto-grants-1995_06 |
|---|
