4-Nitrobenzamide → 4-Aminobenzamide
反応式
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:10])=[O:9])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:10])=[O:9])=[CH:6][CH:5]=1参加物
4
実験手順
In 100 ml of absolute ethanol, 8.35 g of the compound of Example II was hydrogenated over 2 spatulas-full of 10% Pd/C in a Parr apparatus at ca 40 lbs/in2 for 3-4 hrs. Under a nitrogen blanket, the catalyst was filtered off through a Celite pad (sintered glass funnel), which was washed with two volumes of ethanol. Evaporation gave ca 7.2 g of a brown oil.
後処理
- customin2 for 3-4 hrs
- filtrationUnder a nitrogen blanket, the catalyst was filtered off through a Celite pad (sintered glass funnel), which
- washwas washed with two volumes of ethanol
- customEvaporation
出典と根拠
- ORDレコード
- ord-3b2ae0a86cb24970997363fb693d602b
- 出典データセット
- uspto-grants-1980_11
- 特許番号
- US04235969
反応ノート
読み込み中…