化工社化工社 化学情報印刷レポート · 研究参考用
3'-(Trifluoromethyl)acetophenone → 3-Dimethylamino-3'-trifluoromethylacrylophenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3'-(Trifluoromethyl)acetophenone | HCID 67682 | — |
| 反応物 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 生成物 | 3-Dimethylamino-3'-trifluoromethylacrylophenone | HCID 730024 | — |
反応手順
A reaction mixture of 50 g. of m-trifluoromethylacetophenone and 50 ml. of dimethylformamide dimethylacetal is refluxed for 16 hours under anhydrous conditions and then evaporated in vacuo to a thick orange-red oil. Hexane is added, the mixture is chilled and the desired product is collected by filtration as yellow crystals, m.p. 60.5°-62° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04236005 |
| 出典データセット | uspto-grants-1980_11 |
| ORD ID | ord-563b351be4444408818fafacaa17972b |
| 出典メモ | uspto-grants-1980_11 |