反应详情

A reaction mixture of 50 g. of m-trifluoromethylacetophenone and 50 ml. of dimethylformamide dimethylacetal is refluxed for 16 hours under anhydrous conditions and then evaporated in vacuo to a thick orange-red oil. Hexane is added, the mixture is chilled and the desired product is collected by filtration as yellow crystals, m.p. 60.5°-62° C.

1. additionA reaction mixture of 50 g
2. customevaporated in vacuo to a thick orange-red oil
3. additionHexane is added
4. temperaturethe mixture is chilled
5. filtrationthe desired product is collected by filtration as yellow crystals, m.p. 60.5°-62° C.