Benzoyl Peroxide → 5-(3-Bromomethylphenyl)isoxazole
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[O:12][N:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[Br:13]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:13][CH2:1][C:2]1[CH:3]=[C:4]([C:8]2[O:12][N:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1参加物
5
実験手順
106 mg of 5-(3-methylphenyl)isoxazole, 119 mg of N-bromosuccinimide and 2 mg of benzoyl peroxide were dissolved in 10 ml of carbon tetrachloride, and the solution was refluxed for 3 hours with stirring. After cooling, the precipitate was separated by filtration, and concentrated under reduced pressure to give 5-(3-bromomethylphenyl)isoxazole as a pale yellow oily product.
後処理
- temperaturethe solution was refluxed for 3 hours
- temperatureAfter cooling
- customthe precipitate was separated by filtration
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-3b6a53edcdec44a5aea4950aa6624dc7
- 出典データセット
- uspto-grants-1993_08
- 特許番号
- US05234946
反応ノート
読み込み中…