Hydrochloric Acid → 6-Tri-fluoromethoxy-2,4-benzothiazolediamine
反応式
[F:1][C:2]([F:18])([F:17])[O:3][C:4]1[CH:13]=[C:12]([N+:14]([O-])=O)[C:7]2[N:8]=[C:9]([NH2:11])[S:10][C:6]=2[CH:5]=1.Cl.C(O)C>[Fe].O>[F:18][C:2]([F:1])([F:17])[O:3][C:4]1[CH:5]=[C:6]2[S:10][C:9]([NH2:11])=[N:8][C:7]2=[C:12]([NH2:14])[CH:13]=1参加物
6
実験手順
The procedure is as Example 7, starting with 6-trifluoromethoxy-4-nitro-2-benzothiazolamine, iron powder, concentrated hydrochloric acid and ethanol having a water content of 50% (vol./vol.). After purification on a column of silica with a mixture of cyclohexane and ethyl acetate (10:90 by volume) as eluant, a white solid (1.5 g) is recovered, which solid is recrystallized in toluene (130 cc) to obtain 6-tri-fluoromethoxy-2,4-benzothiazolediamine (1 g), m.p. 206° C.
後処理
- customAfter purification on a column of silica
- additionwith a mixture of cyclohexane and ethyl acetate (10:90 by volume) as eluant
- customa white solid (1.5 g) is recovered
- customwhich solid is recrystallized in toluene (130 cc)
出典と根拠
- ORDレコード
- ord-27d89115e4494f5f97657bbdda12bec5
- 出典データセット
- uspto-grants-1993_08
- 特許番号
- US05236940
反応ノート
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