3,4-Dimethoxy-5-nitrobenzophenone → 3,4-Dihydroxy-5-nitrobenzophenone

HRID 2254713ノート

反応式

HRID 2254713 の反応式
C[O:2][C:3]1[CH:4]=[C:5]([CH:14]=[C:15]([N+:19]([O-:21])=[O:20])[C:16]=1[O:17]C)[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]>C(O)(=O)C.Br>[OH:2][C:3]1[CH:4]=[C:5]([CH:14]=[C:15]([N+:19]([O-:21])=[O:20])[C:16]=1[OH:17])[C:6]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)=[O:7]

参加物

4

反応物 1

HCID 214590553,4-Dimethoxy-5-nitrobenzophenone

生成物 1

HCID 57479693,4-Dihydroxy-5-nitrobenzophenone

試薬・触媒・溶媒 2

HCID 176Acetic Acid溶媒HCID 260Hydrogen Bromide溶媒

実験手順

0.5 g of 3,4-dimethoxy-5-nitrobenzophenone is stirred at 100° for 30 hours in a mixture of 4 ml of acetic acid and 4 ml of 48 percent aqueous hydrobromic acid. The reaction mixture is subsequently evaporated to dryness. The residue is taken up in methylene chloride. It is washed with water, dried over sodium sulfate and evaporated. After recrystallization from methylene chloride/hexane there is obtained 3,4-dihydroxy-5-nitrobenzophenone of m.p. 132°.

後処理

  1. customThe reaction mixture is subsequently evaporated to dryness
  2. washIt is washed with water
  3. dry with materialdried over sodium sulfate
  4. customevaporated
  5. customAfter recrystallization from methylene chloride/hexane there

出典と根拠

ORDレコード
ord-2901d89e5713419fa99797df468926c0
出典データセット
uspto-grants-1993_08
特許番号
US05236952

反応ノート

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