1-Benzyl-5-methyloctahydropyrrolo[3,4-b]pyrrole → 5-Methyl-octahydropyrrolo(3,4-b)pyrrole
反応式
C([N:8]1[CH2:15][CH2:14][CH:13]2[CH:9]1[CH2:10][N:11]([CH3:16])[CH2:12]2)C1C=CC=CC=1>C(O)C.[Pd]>[CH3:16][N:11]1[CH2:10][CH:9]2[CH:13]([CH2:14][CH2:15][NH:8]2)[CH2:12]1参加物
4
実験手順
10.3 g (47.6 mmol) of 2-benzyl-7-methyl-2,7 -diazabicyclo[3.3.0]octane in 200 ml of ethanol are hydrogenated at 100° C. and 100 bar on 2.5 g of palladium-active carbon (10% Pd). The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled.
後処理
- customare hydrogenated at 100° C.
- filtrationThe catalyst is filtered off with suction
- concentrationthe filtrate is concentrated
- distillationthe residue is distilled
出典と根拠
- ORDレコード
- ord-9e7873da452e4c47a33aaa11fc89d22f
- 出典データセット
- uspto-grants-1993_08
- 特許番号
- US05241076
反応ノート
読み込み中…