2-Methoxyethylamine → HCID 54038932、化合物
反応式
CO[C:3](=[O:18])[CH2:4][CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9].[CH3:19][O:20][CH2:21][CH2:22][NH2:23]>C(O)C>[CH3:19][O:20][CH2:21][CH2:22][NH:23][C:3](=[O:18])[CH2:4][CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:9]参加物
4
実験手順
5.02 g of 4-benzyloxycarbonylaminobutyric acid methyl ester are stirred under reflux in 35 ml of ethanol with 15 ml of 2-methoxyethylamine for 5 days. The reaction mixture is concentrated by evaporation and the residue is purified by means of FC (240 g of silica gel, dichloromethane/methanol=95:5). The title compound is obtained: Rf (dichloromethane/methanol=95:5)=0.33.
後処理
- concentrationThe reaction mixture is concentrated by evaporation
- customthe residue is purified by means of FC (240 g of silica gel, dichloromethane/methanol=95:5)
出典と根拠
- ORDレコード
- ord-7e6c22af3ae9431c8683307f6cd6657a
- 出典データセット
- uspto-grants-1997_08
- 特許番号
- US05654445
反応ノート
読み込み中…