Allyl bromide → 2-(2-Propen-1-ylthio)pyrazine
反応式
[SH:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1.[CH2:8](Br)[CH:9]=[CH2:10]>C(N(CC)CC)C>[CH2:10]([S:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1)[CH:9]=[CH2:8]参加物
4
反応条件
- 温度
- 50 °C
実験手順
6.57 g of 2-mercaptopyrazine prepared in Reference Example 1 was dissolved in 80 ml of dimethylformaind and 8.6 ml of triethylamine was added thereto. 6.84 ml of allyl bromide was added to the solution and the mixture was stirred at 50° C. for 2 hours. 500 ml of ice water was added to the reaction solution and the resulting mixture was extracted with diethylether and concentrated. The residues were distilled under vacuum to give 7.85 g(85%) of oily pale yellow liquid.
後処理
- additionwas added
- extractionthe resulting mixture was extracted with diethylether
- concentrationconcentrated
- distillationThe residues were distilled under vacuum
出典と根拠
- ORDレコード
- ord-641f590ead084f438b6faee712ba37ba
- 出典データセット
- uspto-grants-1997_08
- 特許番号
- US05658913
反応ノート
読み込み中…